In a recent study, researchers from the Indian Institute of Technology (ISM) at the Indian Institute of Technology developed a blood glucose sensor that uses light for blood glucose monitoring. The researchers said the sensor can measure a variety of blood glucose levels ranging from 10-200 mg/dl (mg/dl). The average blood glucose level measured by fasting in healthy adults is between 70-120 mg/dl (mg/dl).
Photosensors for analyzing biological samples are becoming increasingly popular because of their ease of use and without damaging test samples. This type of sensor can be immersed in a sample to detect the target compound. The researchers in this study are based on the working principle of a halo resonator that tracks small changes in blood glucose levels.
Try to think of a halo resonator as an "Echo Gallery." On the echo gallery, the sound waves from the whisper of the whisper are magnified and will soon become a loud noise. Also, in an optical resonator, light waves of a specific wavelength passing through the resonator are enhanced due to repeated internal reflection and interference. The aura resonator is very sensitive and does not become distorted by the presence of other impurities, thus providing accurate readings. A halo resonator based device can be used to measure a variety of molecules and chemicals, including gas phase conditions.
Halo resonators are often used for the study of specific biomolecules, such as proteins, bacteria, cells or DNA samples, to see how they interact and deviate from light. The presence of such biological particles alters the refractive index of the medium in which they are present, which can cause resonance conditions in the resonator to deviate when the resonator is immersed in the medium. The change in resonant wavelength is related to the amount of biological particles in the medium.
In this study, researchers used optical resonators to measure glucose levels in blood samples. The presence of glucose molecules alters the light output of the resonator, depending on the amount of glucose molecules, which in turn helps researchers measure glucose levels indirectly by measuring light output.
The researchers used two types of waveguides, and the sensor device was able to confine the light to a specific direction. The slot waveguide is formed into a narrow slit in the rectangular tube, and the light wave passes; the ridge of the ridge waveguide is on the opposite faces of the rectangular tube. Researchers have observed that slit-based resonators are six times more sensitive than ridge-based resonators. Sensors with both configurations are able to detect minimal changes in glucose concentration in the sample.
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